Tuxera NTFS is not a part of the Mac system that comes with your Mac by default. It is an NTFS for Mac utility that gives you read & write access to a Windows NTFS formatted drive on your Mac. Without an NTFS for Mac utility, you cannot transfer, copy to, or deleted files to a drive with the NTFS file system on your macOS devices.
If you needn't perform any writing actions to an NTFS drive on your Mac, you can uninstall it on your Mac to free up space on Macintosh HD straightforwardly. Either the included Tuxera uninstaller or iBoysoft MagicMenu works fine in the uninstallation work.
iBoysoft MagicMenu, however, is more suggested because it not only deletes the Tuxera application but also clears the garbage files at the same time.